| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 11/04/25 20.00 | NEC Nijmwegen | RKC Waalwijk | 2:1 |
| 12/04/25 16.30 | Fortuna Sittard | Feyenoord Rotterdam | 0:2 |
| 12/04/25 18.45 | Sparta Rotterdam | SC Heerenveen | 3:1 |
| 12/04/25 20.00 | PSV Eindhoven | Almere City FC | 5:0 |
| 12/04/25 21.00 | NAC Breda | Go Ahead Eagles Deventer | 1:1 |
| 13/04/25 12.15 | FC Utrecht | FC Groningen | 3:1 |
| 13/04/25 14.30 | Heracles Almelo | AZ Alkmaar | 1:0 |
| 13/04/25 14.30 | PEC Zwolle | FC Twente Enschede | 1:1 |
| 13/04/25 16.45 | Willem II Tilburg | Ajax Amsterdam | 1:2 |